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R client for bioc-on-ice: Bioconductor annotation as versioned Parquet releases, queried with DuckDB
Durable messaging channels for pi-durable hosts
Field notes on R's runtime, and the design taste that follows.
Agent harness for learning difficult things.
A template for developing DuckDB extensions in Zig
Performing highly efficient genome scans for local adaptation with R package pcadapt v4
A software package for local ancestry inference and haplotype phasing
High-performance Piecewise Geometric Model (PGM) learned index implementation in pure Rust with strict epsilon error guarantees
exact tokenizers ids, as fast as the hardware allows
C++ Parallel Computing and Asynchronous Networking Framework
open weight open harness AI with rstudio targeting AnVIL T4 GPU
Low-latency NUMA-aware fork-join thread-pool with zero allocations, syscalls, CAS, or false-sharing on the hot path for C++, C, Rust, Zig & Mojo 🍴
Massively concurrent background loops for your agents
R-native Unix system administration: umbrella repo (architecture and docs)
Detecting contamination in NGS data and multi-species analysis
Fast Rust reimplementation of Ensembl VEP (Variant Effect Predictor): same flags and output formats, 100x+ faster
Fil-C as a Nix C/C++ toolchain and cross platform
An R package to build fast interactive data analysis pipelines that scale.